Two clinical studies done at Kilpauk medical college
Tolenorm oil Augments Repigmentation (study period 3 years)
|Duration||Extent of repigmentation||% of patients|
Percentage of re pigmentation proves the efficacy of Tolenorm in the management of vitiligo
90% Re-pigmentation within 15 months with the use of Tolenorm (Study period 15 months)
60 patients with various types of Vitiligo were treated with both Tolenorm oil and Tolenorm ointment for a period of 15 months.
Patients were reviewed every fortnight and they were also clinically assessed for any untoward side effects as the drugs were used for a long time.
It was clinically proved that both Tolenorm oil and Tolenorm ointment were non toxic and safe for long term use.
|Time in Months||Percentage of Repigmentation|
Nearly complete repigmentation is possible with topical Tolenorm
Significant Increase in Tyrosinase Activity with Topical Tolenorm
Effect of Tolenorm on tyrosinase activity in melanocytes-B16F10 cell line
|Time in minutes||Enzyme activity (IU/ml)|
The study reveals the effectiveness of Tolenorm oil on the tyrosinase enzyme activity.